FEMTO Engineering is an R&D center of the foundation FC Innov

From science to society

Biomedical

Advanced technologies for medical devices, biological analysis and life sciences.

The biomedical field requires precision and reliability that few technologies can guarantee. FEMTO Engineering supports manufacturers, laboratories and health stakeholders in the development of innovative biomedical devices, microfluidic systems and technologies for life sciences.

Drawing on skills in microfabrication, surface treatment, instrumentation, and characterization, the team operates from feasibility studies to the production of prototypes and functional demonstrators—by accessing FEMTO-ST’s technological platforms to transform research concepts into concrete solutions for diagnostics, biological analysis and medical devices.

For what needs?

Design a medical device that you cannot manufacture internally

You are developing a component or system intended for medical use—sensor, probe, lab-on-chip, diagnostic device—but you do not have access to a clean room or the microfabrication processes needed for its production.

Quickly move from a concept to a testable prototype

You have validated an idea on paper or in simulation. You need a first physical device to test the performance, identify the necessary adjustments and prepare for a qualification phase.

Integrate microfluidic functions into an existing system

You want to miniaturize an analysis step, handle very small volumes of biological liquids or integrate channels and reactors into a compact device for diagnosis or research.

Characterize biological interactions with precision tools

You need to measure molecular interactions, detect biological targets in fluids or validate the properties of biofunctionalized surfaces with equipment that you do not have in your company.

Our services

Feasibility study and tests

Assessment of material/ process/ biological use compatibility, first controlled environment tests, results report.

Development of processes

Development of manufacturing parameters adapted to biomedical constraints, optimization of results, documentation of the developed process.

Production of medical devices

Design and manufacture of components or systems integrating biocompatibility constraints and the requirements of the medical sector.

Manufacture of small and medium series

Production in limited quantities for qualification, clinical validation or marketing phases.

On-demand technological services

Access to FEMTO Engineering equipment and expertise for occasional or recurring needs, with dedicated technical support.

Application examples

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Diagnosis & biological analysis

SPR biochips for the detection of proteins and blood microparticles, microfluidic reactors for the analysis of biological liquids, systems for virological diagnosis. Tools that enable detection, measurement and analysis in very low volumes with research-level precision.

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Implantable devices & surgery

Cutting stents, machining of polymers for implantable heart probes, cupules micro-machining for cell culture. Contact-free processes without thermal contamination, on biocompatible materials that do not tolerate conventional processes.

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Medical instrumentation

Optical probes, fiber optic sensors, portable demonstrators with integrated sensors and actuators. For manufacturers who develop medical equipment and need custom miniaturized components.

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Microfluidics & Lab-on-Chip

Microfluidic channels in biocompatible materials, pore-controlled filtration membranes, hemostasis control devices. For teams working on the miniaturization of biological analyses and the development of point-of-care devices.

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Life sciences & research

Polymer membranes for cell culture, custom wells and microwells from Ø 10 μm to 300 μm, nanocharacterization by AFM. For laboratories and research teams looking for materials and tools made to precise specifications.

A partner for your innovation projects

FEMTO Engineering holds a rare position: it is an engineering center capable of covering the entire development of a biomedical device, from design to manufacturing, relying on equipment and expertise issued from academic research at an international level.

For an industrial company or a project leader in the medical sector, it is the possibility to access advanced technologies—microfabrication, laser, SPR, microfluidic—without having to internalize them, with a team who understands both scientific constraints and field requirements.

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Our technical means

Platform
MicroRobotex

The precision microrobotics platform for micrometer-scale manipulation and assembly.

Platform
MIMENTO

MIcrofabrication for MEchanics, Nanosciences, Thermics, and Optics
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MIMENTO clean room

Microfabrication in a controlled environment ISO 5 to 7, ISO 9001. Photolithography, plasma etching, thin film deposition, connectors and packaging.

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Femtosecond laser for biomedical applications

Cutting stents, implantable polymers machining, production of microfluidic circuits, filtration membranes, precision drilling in biocompatible materials.

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SPR imaging and nanocharacterization

SPR imaging instrument, atomic force microscope (AFM), SUPRA-MS analysis by coupling biochips / mass spectrometry (CLIPP proteomics platform).

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Precision microfluidic structures

100 μm diameter channels in biocompatible materials, Ø 10 μm to 300 μm wells, membranes with submicronic and micronic pores by femtosecond laser.

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Coatings and biofunctionalization

Specific deposits of ZrO2, SiO2, TiO2, biofunctionalization of surfaces for biological analysis and molecular detection applications.

The benefits of this technology

Manufacturing in a controlled sterile environment (ISO cleanroom 5 to 7)

Processes compatible with biocompatible materials and medical requirements

Precision at the micrometric and nanometric scales

Cutting and machining without contact or thermal contamination

Process reproducibility guaranteed by ISO 9001 standards

A few realizations

MIMEDI

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Cutting of glasses and transparent materials

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Biomedical characterization platforms

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BioMEMS & NEMS

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Microfluidics & Lab-on-Chip

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SPR biochips for proteomic analysis

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Biomedical engineering

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Devices for cell sorting

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Contact us

Rabah Zeggari
Rabah ZEGGARI
PhD Cleanroom Microfabrication Engineer BioMEMS & NEMS
+33 (0)3 63 08 24 82
FEMTO Engineering
Bâtiment TEMIS 15B avenue des Montboucons – 25000 BESANÇON

Partners and associated ecosystem

Logo Bionoveo
Bionoveo
CEA-logo
CEA
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FEMTO-ST Institute
Latest news Biomedical
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October 13, 2022

Closure of the MiMédI (Microtechniques for Innovative Medicines) project

Vous développez un dispositif médical ou un système d'analyse biologique ?

Décrivez-nous votre besoin : matériau, fonction, contraintes d'usage. On évalue la faisabilité et on vous répond rapidement.
4-step method

Our support method

1
Study & feasibility
Analyse, frame and validate your technical assumptions
2
Technological development
Design and experiment solutions adapted to your constraints.
3
Prototyping & pre-series
Transform the concept into a functional object ready to evolve.
4
Industrial transfer
Train your teams and integrate the processes for good.

Research-based engineering, geared towards industry

FEMTO Engineering supports the companies in the development of advanced technologies by relying on the scientific excellence of the FEMTO-ST institute. FEMTO Engineering has a dedicated team of engineers and specialized experts at the service of your innovation projects, who are immersed among the FEMTO-ST research teams.

Our role: to transform the academic research results into concrete industrial solutions.

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Financial support from the Région Bourgogne-Franche-Comté

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Carnot accreditation

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Eligible for Research Tax Credit (CIR)

Contact the department Biomedical